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APOE expression and secretion are modulated by mitochondrial dysfunction.
Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, Shanbhag V, Petris M, Senoo N, Kandasamy S, Claypool SM, Barrientos A, Wingo A, Wingo TS, Rangaraju S, Levey AI, Werner E, Faundez V. Wynne ME, et al. Elife. 2023 May 12;12:e85779. doi: 10.7554/eLife.85779. Elife. 2023. PMID: 37171075 Free PMC article.
Shared mechanisms across the major psychiatric and neurodegenerative diseases.
Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Wingo TS, et al. Among authors: wynne me. Nat Commun. 2022 Jul 26;13(1):4314. doi: 10.1038/s41467-022-31873-5. Nat Commun. 2022. PMID: 35882878 Free PMC article.
Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus.
Gokhale A, Lee CE, Zlatic SA, Freeman AAH, Shearing N, Hartwig C, Ogunbona O, Bassell JL, Wynne ME, Werner E, Xu C, Wen Z, Duong D, Seyfried NT, Bearden CE, Oláh VJ, Rowan MJM, Glausier JR, Lewis DA, Faundez V. Gokhale A, et al. Among authors: wynne me. J Neurosci. 2021 Aug 4;41(31):6596-6616. doi: 10.1523/JNEUROSCI.2197-20.2021. Epub 2021 Jul 14. J Neurosci. 2021. PMID: 34261699 Free PMC article.